On some systems, where the default suspend mode is "s2idle", the system may not resume properly due to a known timing issue in the kernel. The suspend mode can be verified by reading the contents of the file /sys/power/mem_sleep. The following upstream kernel changes have been proposed to fix the issue:

https://lore.kernel.org/linux-pci/20190927090202.1468-1-drake@endlessm.com/

https://lore.kernel.org/linux-pci/20190821124519.71594-1-mika.westerberg@linux.intel.com/

In the interim, the default suspend mode on the affected systems should be set to "deep" using the kernel command line parameter "mem_sleep_default" -

mem_sleep_default=deep